On the impossibility of faithfully storing single-photons with the three-pulse photon echo

The three-pulse photon echo is a well-known technique to store intense light pulses in an inhomogeneously broadened atomic ensemble. This protocol is attractive because it is relatively simple and it is well suited for the storage of multiple temporal modes. Furthermore, it offers very long storage times, greater than the phase relaxation time. Here, we consider the three-pulse photon echo in both two- and three-level systems as a potential technique for the storage of light at the single-photon level. By explicit calculations, we show that the ratio between the echo signal corresponding to a single-photon input and the noise is smaller than one. This severely limits the achievable fidelity of the quantum state storage, making the three-pulse photon echo unsuitable for single-photon quantum memory.Comment: 6 pages, 4 figure

Electronic structure of β\beta-SiAlON: effect of varying Al/O concentration at finite temperatures relevant for thermal quenchin

$\beta$-Si$_{6-z}$Al$_{z}$O$_{z}$N$_{8-z}$ is a prominent example of systems suitable as hosts for creating materials for light-emitting diodes. In this work, the electronic structure of a series of ordered and disordered $\beta$-Si$_{6-z}$Al$_{z}$O$_{z}$N$_{8-z}$ systems is investigated by means of ab initio calculations, using the FLAPW and the Green function KKR methods. Finite temperature effects are included within the alloy analogy model. We found that the trends with the Al/O doping are similar for ordered and disordered structures. The electronic band gap decreases with increasing $z$ by about 1 eV when going from $z$=0 to $z$=2. The optical gap decreases analogously as the electronic band gap. The changes in the density of states (DOS) at Si and N atoms introduced by doping $\beta$-Si$_{3}$N$_{4}$ with Al and O are comparable to the DOS at Al and O atoms themselves. The bottom of the conduction band in $\beta$-Si$_{6-z}$Al$_{z}$O$_{z}$N$_{8-z}$ is formed by extended states residing on all atomic types. Increasing the temperature leads to a shift of the bottom of the conduction band to lower energies. The amount of this shift increases with increasing doping $z$.Comment: 11 pages, 11 figures, 1 tabl

Sentinel lymph node mapping and intraoperative assessment in a prospective, international, multicentre, observational trial of patients with cervical cancer: The SENTIX trial

Background: SENTIX (ENGOT-CX2/CEEGOG-CX1) is an international, multi centre, prospective observational trial evaluating sentinel lymph node (SLN) biopsy without pelvic lymph node dissection in patients with early-stage cervical cancer. We report the final preplanned analysis of the secondary end-points: SLN mapping and outcomes of intraoperative SLN pathology. Methods: Forty-seven sites (18 countries) with experience of SLN biopsy participated in SENTIX. We preregistered patients with stage IA1/lymphovascular space invasion-positive to IB2 (4 cm or smaller or 2 cm or smaller for fertility-sparing treatment) cervical cancer without suspicious lymph nodes on imaging before surgery. SLN frozen section assessment and pathological ultrastaging were mandatory. Patients were registered postoperatively if SLN were bilaterally detected in the pelvis, and frozen sections were negative. Trial registration: ClinicalTrials.gov (NCT02494063). Results: We analysed data for 395 preregistered patients. Bilateral detection was achieved in 91% (355/395), and it was unaffected by tumour size, tumour stage or body mass index, but it was lower in older patients, in patients who underwent open surgery, and in sites with fewer cases. No SLN were found outside the seven anatomical pelvic regions. Most SLN and positive SLN were localised below the common iliac artery bifurcation. Single positive SLN above the iliac bifurcation were found in 2% of cases. Frozen sections failed to detect 54% of positive lymph nodes (pN1), including 28% of cases with macrometastases and 90% with micrometastases. Interpretation: SLN biopsy can achieve high bilateral SLN detection in patients with tumours of 4 cm or smaller. At experienced centres, all SLN were found in the pelvis, and most were located below the iliac vessel bifurcation. SLN frozen section assessment is an unreliable tool for intraoperative triage because it only detects about half of N1 cases. (C) 2020 The Author(s). Published by Elsevier Ltd

Central Pathology Review in SENTIX, a Prospective Observational International Study on Sentinel Lymph Node Biopsy in Patients with Early-Stage Cervical Cancer (ENGOT-CX2)

The quality of pathological assessment is crucial for the safety of patients with cervical cancer if pelvic lymph node dissection is to be replaced by sentinel lymph node (SLN) biopsy. Central pathology review of SLN pathological ultrastaging was conducted in the prospective SENTIX/European Network of Gynaecological Oncological Trial (ENGOT)-CX2 study. All specimens from at least two patients per site were submitted for the central review. For cases with major or critical deviations, the sites were requested to submit all samples from all additional patients for second-round assessment. From the group of 300 patients, samples from 83 cases from 37 sites were reviewed in the first round. Minor, major, critical, and no deviations were identified in 28%, 19%, 14%, and 39% of cases, respectively. Samples from 26 patients were submitted for the second-round review, with only two major deviations found. In conclusion, a high rate of major or critical deviations was identified in the first round of the central pathology review (28% of samples). This reflects a substantial heterogeneity in current practice, despite trial protocol requirements. The importance of the central review conducted prospectively at the early phase of the trial is demonstrated by a substantial improvement of SLN ultrastaging quality in the second-round review

Retinal status analysis method based on feature extraction and quantitative grading in OCT images

Background: Optical coherence tomography (OCT) is widely used in ophthalmology for viewing the morphology of the retina, which is important for disease detection and assessing therapeutic effect. The diagnosis of retinal diseases is based primarily on the subjective analysis of OCT images by trained ophthalmologists. This paper describes an OCT images automatic analysis method for computer-aided disease diagnosis and it is a critical part of the eye fundus diagnosis. Methods: This study analyzed 300 OCT images acquired by Optovue Avanti RTVue XR (Optovue Corp., Fremont, CA). Firstly, the normal retinal reference model based on retinal boundaries was presented. Subsequently, two kinds of quantitative methods based on geometric features and morphological features were proposed. This paper put forward a retinal abnormal grading decision-making method which was used in actual analysis and evaluation of multiple OCT images. Results: This paper showed detailed analysis process by four retinal OCT images with different abnormal degrees. The final grading results verified that the analysis method can distinguish abnormal severity and lesion regions. This paper presented the simulation of the 150 test images, where the results of analysis of retinal status showed that the sensitivity was 0.94 and specificity was 0.92.The proposed method can speed up diagnostic process and objectively evaluate the retinal status. Conclusions: This paper aims on studies of retinal status automatic analysis method based on feature extraction and quantitative grading in OCT images. The proposed method can obtain the parameters and the features that are associated with retinal morphology. Quantitative analysis and evaluation of these features are combined with reference model which can realize the target image abnormal judgment and provide a reference for disease diagnosi

Coherent control, quantum memories and quantum repeaters

In the domain of quantum communication, one of the main challenges is the distribution of entanglement over long distances. A scheme, the so-called quantum repeater, has been proposed in order to overcome the problem of channel losses. In this thesis we adresse different problems related to quantum repeaters, both theoretically and experimentally. We present an alternative scheme of quantum repeater based on atomic ensembles and linear optics. It is based on the use of a qubit amplifier and two photon interference. The main features of the protocol are that the distributed entangled state does not need post selection and the entanglement distribution rates approach the optimal rates one might expect from quantum repeaters using probabilistic swapping. An important concern of the whole class of quantum repeaters based on one photon interference is the phase stability in the communication channels. We performed an experiment evaluating the realistic phase noise in installed optical fibers in the Geneva urban area. We found fluctuations of order of 0.1 rad on the time scale of order of 100 $mu$s. The feasibility of the phase stabilization is discussed. One of the essential building blocks of quantum repeater is a quantum memory. We focus our attention on quantum memories based on solid state atomic ensembles and photon echo like techniques. In particular, we show, that the atomic coherence in eryso can be controlled to a very high degree using an external electric field. This allowed us to implement the CRIB protocol in this material and realize the first storage of light at the single photon level at telecommunication wavelength. A necessary step for the implementation of CRIB and AFC storage protocols, in order to achieve long storage times and unit efficiencies, is the use of control light pulses. We developped a numerical Maxwell-Bloch simulator allowing us to study a coherent control of atomic excitations. In particular, we investigate the use of adiabatic chirped pulses in the context of AFC protocol. We study the relationship between the pulse characteristics and the echo properties. The comparison with the conventional $pi$ pulses and the impacts on the multimode capacity of the AFC protocol are also discussed

Mimicking Dirac fields in curved spacetime with fermions in lattices with non-unitary tunneling amplitudes

10.1088/1751-8113/48/16/165001Journal of Physics A: Mathematical and Theoretical481

Laendlicher Raum ohne Landwirtschaft?: Folgen d. Rueckzugs d. Landwirtschaft aus Mittelgebirgsregionen am Beispiel d. Nordeifel

SIGLEAvailable from Bibliothek des Instituts fuer Weltwirtschaft, ZBW, Duesternbrook Weg 120, D-24105 Kiel A 162145 / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Automatic detection of the macula in retinal fundus images using multilevel thresholding

The paper proposes a novel method for detection of macula in medical image of human eye – retinal fundus images, that can be used in ophthalmology for detecting various eye’s diseases as glaucoma, diabetic retinopathy or macula oedema. The method utilizes an approach of multilevel thresholding ofred channel of fundus retinal image. Subsequently, thethresholded layers are preprocessed by application of median blur filter. And algorithm for ellipse detection from OpenCVlibrary is used on all thresholding level. Then proposed technique analyzes detection and evaluates position of macula in fundus image. The precision of the method is evaluated on dataset from public fundus image library DRIVE. The results were 100% for image with visible macula